Sherfane Rutherford is a Guyanese cricketer. He made his first-class debut for Guyana in the 2016-17 Regional Four Day Competition on 15 April 2017. He made his List A debut for Guyana in the 2017-18 Regional Super50 on 31 January 2018.
In June 2018, he was named in the Cricket West Indies B Team squad for the inaugural edition of the Canada tournament. He was the leading run-scorer in the tournament for the Cricket West Indies B Team, with 230 runs in eight matches.
He made his Twenty20 debut for Guyana Amazon Warriors in the 2018 Caribbean Premier League on 9 August 2018.
In October 2018, he was named in the West Indies’ Twenty20 International (T20I) squad for series against India. Later in the same month, he was named in the squad for the Khulna Titans team, following the draft for the 201-19 Bangladesh Premier